Journal: Nucleic Acids Research
Article Title: PhoP-regulated VirK acts as an accessory factor to maintain virulence in polymyxin-resistant Klebsiella pneumoniae
doi: 10.1093/nar/gkag290
Figure Lengend Snippet: Sequence and structure comparison of VirK (from K. pneumoniae ATCC BAA2146) and YbjX (from E. coli K-12 ) proteins. ( A ) Alignment of the amino acid sequence of VirK ( Q ) with that of YbjX ( T ); ( B ) Comparison of the protein structures of VirK and YbjX. Amino acid sequences and structures were compared using the foldseek server . The protein structure of YbjX was obtained from the AFDB database (AFDB accession: AF- P75829 -F1).
Article Snippet: Results from K. pneumoniae ATCC BAA2146 serial strains suggested that virK deficiency resulted in a modest reduction in bacterial virulence, while complementation partially restored this phenotype.
Techniques: Sequencing, Comparison